How looking at a building can trigger headaches, seizures
http://edition.cnn.com/2017/06/08/health/building-patterns-headaches-partner/index.html
The article theoretically explains why urban life triggers headache. But, the core reason of headache seems to be seeing stripes. It means headache would be eased, if stripes are erased from surface of the buildings.
Designers will have to make an effort to reduce as many stripes as they can.